As the San Francisco 49ers gear up to take on the Chicago Bears, anticipation is building for a thrilling matchup that could have significant playoff implications. Both teams bring unique strengths and challenges to the table, making this an intriguing contest. The 49ers are known for their dynamic offense led by quarterback Brock Purdy and a stout defense, while the Bears will rely on Justin Fields to lead their charge. In this preview, we’ll examine the key factors in the game and offer our predictions on which team is most likely to emerge victorious in this exciting showdown.

49ers vs Bears Picks

🏈 Chicago Bears vs San Francisco 49ers
🕖 When to Watch: 4:25 PM EST
📺 Where to Watch: FOX

✅ PICK: 49ers -3.5 (-115)
✅ PICK: UNDER 47.5 (-189)
✅ PICK: Moneyline First Half – 49ers (-148)

Fun Facts:
👉 Each of the Bears’ last 8 road games have gone UNDER the total points line.
👉 The 49ers have won the first half of each of their last 10 home games against the Bears.